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KMID : 0644120170300010042
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Journal of Oriental Gynecology
2017 Volume.30 No. 1 p.42 ~ p.55
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Trends Analysis of Clinical Studies on Korean Medicine for Infertility
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So Min-Ji
Lee Yoon-Jae
Kim Su-Hyun
Jang Jun-Bock
Hwang Deok-Sang
Kim Dong-Il
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Abstract
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Objectives: This study were investigated clinical studies published in international and Korea's journals to assess the effect of Korean Medicine for infertility.
Methods: PubMed and Oriental Medicine Advanced Searching Integrated System (OASIS) were searched for this review up to Nov 2016.: using terms of 'infertility' and 'subfertile'.
Results: Fifty clinical studies were finally selected. All studies were assessed as the noncomparative studies, and mainly case reports. The year of publication of literatures was the highest at from 2011 to 2015, accounted for 44%. Among 50 studies, there were 5 studies on males, 43 studies on females and 2 studies on both male and female. The number of subjects varies from 1 to 1277. The number of studies with subjects less than 10 was the greatest. Of all the studies, only three were institutional review board (IRB) approved. There were 9 studies that indicated whether the grant was supported. The duration of treatment was between 30 and 360 days, and most cases were within 180 days. Intervention methods were 100% for herb medicine, 40% added on acupuncture, and 29% added on moxibustion.
Conclusions: Further clinical trials of well designed is needed to accumulate enough information to establish the evidence for Korean Medicine for infertility.
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KEYWORD
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Infertility , Clinical Study , Medicine , Korean Traditional
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